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selective a2bar antagonist psb1115  (Tocris)


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    Structured Review

    Tocris selective a2bar antagonist psb1115
    Selective A2bar Antagonist Psb1115, supplied by Tocris, used in various techniques. Bioz Stars score: 99/100, based on 543 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/a2bar+antagonist+psb1115/PSB+1115/pm29898376-154-17-24
    Average 99 stars, based on 543 article reviews
    selective a2bar antagonist psb1115 - by Bioz Stars, 2026-09
    99/100 stars

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    Related Articles

    Concentration Assay:

    Article Title: A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
    Article Snippet: In subsets of experiments, mice were treated with the A2BAR antagonist PSB1115 (10 mg/kg i.p.; Tocris) or the A2BAR agonist BAY 60-6583 (2 mg/kg i.p.; Bayer Healthcare), the A1AR antagonist DPCPX (1 mg/kg i.p.; Tocris), the A3AR antagonist MRS1191 (1 mg/kg i.p.; Sigma-Aldrich), amiloride (10 –3 M, 300 μl intratracheally; Sigma-Aldrich), or zinterol (10 –7 M, 300 μl intratracheally; Tocris); or vehicle ( 13 ).

    Article Title: A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
    Article Snippet: In subsets of experiments, mice were treated with the A2BAR antagonist PSB1115 (10 mg/kg i.p.; Tocris) or the A2BAR agonist BAY 60-6583 (2 mg/kg i.p.; Bayer Healthcare), the A1AR antagonist DPCPX (1 mg/kg i.p.; Tocris), the A3AR antagonist MRS1191 (1 mg/kg i.p.; Sigma-Aldrich), amiloride (10–3 M, 300 μl intratracheally; Sigma-Aldrich), or zinterol (10–7 M, 300 μl intratracheally; Tocris); or vehicle (13).

    Enzyme-linked Immunosorbent Assay:

    Article Title: A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
    Article Snippet: In subsets of experiments, mice were treated with the A2BAR antagonist PSB1115 (10 mg/kg i.p.; Tocris) or the A2BAR agonist BAY 60-6583 (2 mg/kg i.p.; Bayer Healthcare), the A1AR antagonist DPCPX (1 mg/kg i.p.; Tocris), the A3AR antagonist MRS1191 (1 mg/kg i.p.; Sigma-Aldrich), amiloride (10 –3 M, 300 μl intratracheally; Sigma-Aldrich), or zinterol (10 –7 M, 300 μl intratracheally; Tocris); or vehicle ( 13 ).

    Article Title: A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
    Article Snippet: In subsets of experiments, mice were treated with the A2BAR antagonist PSB1115 (10 mg/kg i.p.; Tocris) or the A2BAR agonist BAY 60-6583 (2 mg/kg i.p.; Bayer Healthcare), the A1AR antagonist DPCPX (1 mg/kg i.p.; Tocris), the A3AR antagonist MRS1191 (1 mg/kg i.p.; Sigma-Aldrich), amiloride (10–3 M, 300 μl intratracheally; Sigma-Aldrich), or zinterol (10–7 M, 300 μl intratracheally; Tocris); or vehicle (13).

    MPO Assay:

    Article Title: A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
    Article Snippet: In subsets of experiments, mice were treated with the A2BAR antagonist PSB1115 (10 mg/kg i.p.; Tocris) or the A2BAR agonist BAY 60-6583 (2 mg/kg i.p.; Bayer Healthcare), the A1AR antagonist DPCPX (1 mg/kg i.p.; Tocris), the A3AR antagonist MRS1191 (1 mg/kg i.p.; Sigma-Aldrich), amiloride (10 –3 M, 300 μl intratracheally; Sigma-Aldrich), or zinterol (10 –7 M, 300 μl intratracheally; Tocris); or vehicle ( 13 ).

    Article Title: A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
    Article Snippet: In subsets of experiments, mice were treated with the A2BAR antagonist PSB1115 (10 mg/kg i.p.; Tocris) or the A2BAR agonist BAY 60-6583 (2 mg/kg i.p.; Bayer Healthcare), the A1AR antagonist DPCPX (1 mg/kg i.p.; Tocris), the A3AR antagonist MRS1191 (1 mg/kg i.p.; Sigma-Aldrich), amiloride (10–3 M, 300 μl intratracheally; Sigma-Aldrich), or zinterol (10–7 M, 300 μl intratracheally; Tocris); or vehicle (13).

    Activity Assay:

    Article Title: A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
    Article Snippet: In subsets of experiments, mice were treated with the A2BAR antagonist PSB1115 (10 mg/kg i.p.; Tocris) or the A2BAR agonist BAY 60-6583 (2 mg/kg i.p.; Bayer Healthcare), the A1AR antagonist DPCPX (1 mg/kg i.p.; Tocris), the A3AR antagonist MRS1191 (1 mg/kg i.p.; Sigma-Aldrich), amiloride (10 –3 M, 300 μl intratracheally; Sigma-Aldrich), or zinterol (10 –7 M, 300 μl intratracheally; Tocris); or vehicle ( 13 ).

    Article Title: A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
    Article Snippet: In subsets of experiments, mice were treated with the A2BAR antagonist PSB1115 (10 mg/kg i.p.; Tocris) or the A2BAR agonist BAY 60-6583 (2 mg/kg i.p.; Bayer Healthcare), the A1AR antagonist DPCPX (1 mg/kg i.p.; Tocris), the A3AR antagonist MRS1191 (1 mg/kg i.p.; Sigma-Aldrich), amiloride (10–3 M, 300 μl intratracheally; Sigma-Aldrich), or zinterol (10–7 M, 300 μl intratracheally; Tocris); or vehicle (13).

    Control:

    Article Title: A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
    Article Snippet: In subsets of experiments, mice were treated with the A2BAR antagonist PSB1115 (10 mg/kg i.p.; Tocris) or the A2BAR agonist BAY 60-6583 (2 mg/kg i.p.; Bayer Healthcare), the A1AR antagonist DPCPX (1 mg/kg i.p.; Tocris), the A3AR antagonist MRS1191 (1 mg/kg i.p.; Sigma-Aldrich), amiloride (10 –3 M, 300 μl intratracheally; Sigma-Aldrich), or zinterol (10 –7 M, 300 μl intratracheally; Tocris); or vehicle ( 13 ).

    Article Title: A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
    Article Snippet: In subsets of experiments, mice were treated with the A2BAR antagonist PSB1115 (10 mg/kg i.p.; Tocris) or the A2BAR agonist BAY 60-6583 (2 mg/kg i.p.; Bayer Healthcare), the A1AR antagonist DPCPX (1 mg/kg i.p.; Tocris), the A3AR antagonist MRS1191 (1 mg/kg i.p.; Sigma-Aldrich), amiloride (10–3 M, 300 μl intratracheally; Sigma-Aldrich), or zinterol (10–7 M, 300 μl intratracheally; Tocris); or vehicle (13).

    Staining:

    Article Title: A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
    Article Snippet: In subsets of experiments, mice were treated with the A2BAR antagonist PSB1115 (10 mg/kg i.p.; Tocris) or the A2BAR agonist BAY 60-6583 (2 mg/kg i.p.; Bayer Healthcare), the A1AR antagonist DPCPX (1 mg/kg i.p.; Tocris), the A3AR antagonist MRS1191 (1 mg/kg i.p.; Sigma-Aldrich), amiloride (10 –3 M, 300 μl intratracheally; Sigma-Aldrich), or zinterol (10 –7 M, 300 μl intratracheally; Tocris); or vehicle ( 13 ).

    Article Title: A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
    Article Snippet: In subsets of experiments, mice were treated with the A2BAR antagonist PSB1115 (10 mg/kg i.p.; Tocris) or the A2BAR agonist BAY 60-6583 (2 mg/kg i.p.; Bayer Healthcare), the A1AR antagonist DPCPX (1 mg/kg i.p.; Tocris), the A3AR antagonist MRS1191 (1 mg/kg i.p.; Sigma-Aldrich), amiloride (10–3 M, 300 μl intratracheally; Sigma-Aldrich), or zinterol (10–7 M, 300 μl intratracheally; Tocris); or vehicle (13).

    Isolation:

    Article Title: A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
    Article Snippet: In subsets of experiments, mice were treated with the A2BAR antagonist PSB1115 (10 mg/kg i.p.; Tocris) or the A2BAR agonist BAY 60-6583 (2 mg/kg i.p.; Bayer Healthcare), the A1AR antagonist DPCPX (1 mg/kg i.p.; Tocris), the A3AR antagonist MRS1191 (1 mg/kg i.p.; Sigma-Aldrich), amiloride (10 –3 M, 300 μl intratracheally; Sigma-Aldrich), or zinterol (10 –7 M, 300 μl intratracheally; Tocris); or vehicle ( 13 ).

    Article Title: A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
    Article Snippet: In subsets of experiments, mice were treated with the A2BAR antagonist PSB1115 (10 mg/kg i.p.; Tocris) or the A2BAR agonist BAY 60-6583 (2 mg/kg i.p.; Bayer Healthcare), the A1AR antagonist DPCPX (1 mg/kg i.p.; Tocris), the A3AR antagonist MRS1191 (1 mg/kg i.p.; Sigma-Aldrich), amiloride (10–3 M, 300 μl intratracheally; Sigma-Aldrich), or zinterol (10–7 M, 300 μl intratracheally; Tocris); or vehicle (13).

    Quantitative RT-PCR:

    Article Title: A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
    Article Snippet: In subsets of experiments, mice were treated with the A2BAR antagonist PSB1115 (10 mg/kg i.p.; Tocris) or the A2BAR agonist BAY 60-6583 (2 mg/kg i.p.; Bayer Healthcare), the A1AR antagonist DPCPX (1 mg/kg i.p.; Tocris), the A3AR antagonist MRS1191 (1 mg/kg i.p.; Sigma-Aldrich), amiloride (10 –3 M, 300 μl intratracheally; Sigma-Aldrich), or zinterol (10 –7 M, 300 μl intratracheally; Tocris); or vehicle ( 13 ).

    Article Title: A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
    Article Snippet: In subsets of experiments, mice were treated with the A2BAR antagonist PSB1115 (10 mg/kg i.p.; Tocris) or the A2BAR agonist BAY 60-6583 (2 mg/kg i.p.; Bayer Healthcare), the A1AR antagonist DPCPX (1 mg/kg i.p.; Tocris), the A3AR antagonist MRS1191 (1 mg/kg i.p.; Sigma-Aldrich), amiloride (10–3 M, 300 μl intratracheally; Sigma-Aldrich), or zinterol (10–7 M, 300 μl intratracheally; Tocris); or vehicle (13).

    Gene Expression:

    Article Title: A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
    Article Snippet: In subsets of experiments, mice were treated with the A2BAR antagonist PSB1115 (10 mg/kg i.p.; Tocris) or the A2BAR agonist BAY 60-6583 (2 mg/kg i.p.; Bayer Healthcare), the A1AR antagonist DPCPX (1 mg/kg i.p.; Tocris), the A3AR antagonist MRS1191 (1 mg/kg i.p.; Sigma-Aldrich), amiloride (10 –3 M, 300 μl intratracheally; Sigma-Aldrich), or zinterol (10 –7 M, 300 μl intratracheally; Tocris); or vehicle ( 13 ).

    Article Title: A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
    Article Snippet: In subsets of experiments, mice were treated with the A2BAR antagonist PSB1115 (10 mg/kg i.p.; Tocris) or the A2BAR agonist BAY 60-6583 (2 mg/kg i.p.; Bayer Healthcare), the A1AR antagonist DPCPX (1 mg/kg i.p.; Tocris), the A3AR antagonist MRS1191 (1 mg/kg i.p.; Sigma-Aldrich), amiloride (10–3 M, 300 μl intratracheally; Sigma-Aldrich), or zinterol (10–7 M, 300 μl intratracheally; Tocris); or vehicle (13).

    Real-time Polymerase Chain Reaction:

    Article Title: A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
    Article Snippet: In subsets of experiments, mice were treated with the A2BAR antagonist PSB1115 (10 mg/kg i.p.; Tocris) or the A2BAR agonist BAY 60-6583 (2 mg/kg i.p.; Bayer Healthcare), the A1AR antagonist DPCPX (1 mg/kg i.p.; Tocris), the A3AR antagonist MRS1191 (1 mg/kg i.p.; Sigma-Aldrich), amiloride (10 –3 M, 300 μl intratracheally; Sigma-Aldrich), or zinterol (10 –7 M, 300 μl intratracheally; Tocris); or vehicle ( 13 ).

    Article Title: A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
    Article Snippet: In subsets of experiments, mice were treated with the A2BAR antagonist PSB1115 (10 mg/kg i.p.; Tocris) or the A2BAR agonist BAY 60-6583 (2 mg/kg i.p.; Bayer Healthcare), the A1AR antagonist DPCPX (1 mg/kg i.p.; Tocris), the A3AR antagonist MRS1191 (1 mg/kg i.p.; Sigma-Aldrich), amiloride (10–3 M, 300 μl intratracheally; Sigma-Aldrich), or zinterol (10–7 M, 300 μl intratracheally; Tocris); or vehicle (13).

    Expressing:

    Article Title: A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
    Article Snippet: In subsets of experiments, mice were treated with the A2BAR antagonist PSB1115 (10 mg/kg i.p.; Tocris) or the A2BAR agonist BAY 60-6583 (2 mg/kg i.p.; Bayer Healthcare), the A1AR antagonist DPCPX (1 mg/kg i.p.; Tocris), the A3AR antagonist MRS1191 (1 mg/kg i.p.; Sigma-Aldrich), amiloride (10 –3 M, 300 μl intratracheally; Sigma-Aldrich), or zinterol (10 –7 M, 300 μl intratracheally; Tocris); or vehicle ( 13 ).

    Article Title: A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
    Article Snippet: In subsets of experiments, mice were treated with the A2BAR antagonist PSB1115 (10 mg/kg i.p.; Tocris) or the A2BAR agonist BAY 60-6583 (2 mg/kg i.p.; Bayer Healthcare), the A1AR antagonist DPCPX (1 mg/kg i.p.; Tocris), the A3AR antagonist MRS1191 (1 mg/kg i.p.; Sigma-Aldrich), amiloride (10–3 M, 300 μl intratracheally; Sigma-Aldrich), or zinterol (10–7 M, 300 μl intratracheally; Tocris); or vehicle (13).

    SDS Page:

    Article Title: A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
    Article Snippet: In subsets of experiments, mice were treated with the A2BAR antagonist PSB1115 (10 mg/kg i.p.; Tocris) or the A2BAR agonist BAY 60-6583 (2 mg/kg i.p.; Bayer Healthcare), the A1AR antagonist DPCPX (1 mg/kg i.p.; Tocris), the A3AR antagonist MRS1191 (1 mg/kg i.p.; Sigma-Aldrich), amiloride (10 –3 M, 300 μl intratracheally; Sigma-Aldrich), or zinterol (10 –7 M, 300 μl intratracheally; Tocris); or vehicle ( 13 ).

    Article Title: A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
    Article Snippet: In subsets of experiments, mice were treated with the A2BAR antagonist PSB1115 (10 mg/kg i.p.; Tocris) or the A2BAR agonist BAY 60-6583 (2 mg/kg i.p.; Bayer Healthcare), the A1AR antagonist DPCPX (1 mg/kg i.p.; Tocris), the A3AR antagonist MRS1191 (1 mg/kg i.p.; Sigma-Aldrich), amiloride (10–3 M, 300 μl intratracheally; Sigma-Aldrich), or zinterol (10–7 M, 300 μl intratracheally; Tocris); or vehicle (13).

    Western Blot:

    Article Title: A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
    Article Snippet: In subsets of experiments, mice were treated with the A2BAR antagonist PSB1115 (10 mg/kg i.p.; Tocris) or the A2BAR agonist BAY 60-6583 (2 mg/kg i.p.; Bayer Healthcare), the A1AR antagonist DPCPX (1 mg/kg i.p.; Tocris), the A3AR antagonist MRS1191 (1 mg/kg i.p.; Sigma-Aldrich), amiloride (10 –3 M, 300 μl intratracheally; Sigma-Aldrich), or zinterol (10 –7 M, 300 μl intratracheally; Tocris); or vehicle ( 13 ).

    Article Title: A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
    Article Snippet: In subsets of experiments, mice were treated with the A2BAR antagonist PSB1115 (10 mg/kg i.p.; Tocris) or the A2BAR agonist BAY 60-6583 (2 mg/kg i.p.; Bayer Healthcare), the A1AR antagonist DPCPX (1 mg/kg i.p.; Tocris), the A3AR antagonist MRS1191 (1 mg/kg i.p.; Sigma-Aldrich), amiloride (10–3 M, 300 μl intratracheally; Sigma-Aldrich), or zinterol (10–7 M, 300 μl intratracheally; Tocris); or vehicle (13).

    Clinical Proteomics:

    Article Title: A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
    Article Snippet: In subsets of experiments, mice were treated with the A2BAR antagonist PSB1115 (10 mg/kg i.p.; Tocris) or the A2BAR agonist BAY 60-6583 (2 mg/kg i.p.; Bayer Healthcare), the A1AR antagonist DPCPX (1 mg/kg i.p.; Tocris), the A3AR antagonist MRS1191 (1 mg/kg i.p.; Sigma-Aldrich), amiloride (10 –3 M, 300 μl intratracheally; Sigma-Aldrich), or zinterol (10 –7 M, 300 μl intratracheally; Tocris); or vehicle ( 13 ).

    Article Title: A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
    Article Snippet: In subsets of experiments, mice were treated with the A2BAR antagonist PSB1115 (10 mg/kg i.p.; Tocris) or the A2BAR agonist BAY 60-6583 (2 mg/kg i.p.; Bayer Healthcare), the A1AR antagonist DPCPX (1 mg/kg i.p.; Tocris), the A3AR antagonist MRS1191 (1 mg/kg i.p.; Sigma-Aldrich), amiloride (10–3 M, 300 μl intratracheally; Sigma-Aldrich), or zinterol (10–7 M, 300 μl intratracheally; Tocris); or vehicle (13).



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